meatbat said:
Well, several studies have found that some HUMANS, those who's ancestors survived the Black Death, in one case, have genetic immunity to AIDS. Knowing what those genes are and how they work will help us figure out ways to stop the virus. However, I hate these suggestions that we might be able to "give" people the gene. The is tough.
Really? Can you find that study and post a link? I'd be interested in reading it.
Interesting . . . seeing as how everyone who has a European, Asian, Northern African, or Middle Eastern ancestor is descended from someone who survived the Black Death. So, I'd be interested in seeing that study, too.
Are the words 'in one case' significant here? Maybe I'm reading it wrong.
meatbat said:
Well, several studies have found that some HUMANS, those who's ancestors survived the Black Death, in one case, have genetic immunity to AIDS. Knowing what those genes are and how they work will help us figure out ways to stop the virus. However, I hate these suggestions that we might be able to "give" people the gene. The is tough.
Really? Can you find that study and post a link? I'd be interested in reading it.
He and I saw this on the same PBS show, I think. The best I can find is a partial transcript from the show:
Dr. Stephen O'Brien of the National Institutes of Health in Washington D.C. suggests they were. His work with HIV and the mutated form of the gene CCR5, called "delta 32," led him to Eyam. In 1996, research showed that delta 32 prevents HIV from entering human cells and infecting the body. O'Brien thought this principle could be applied to the plague bacteria, which affects the body in a similar manner. To determine whether the Eyam plague survivors may have carried delta 32, O'Brien tested the DNA of their modern-day descendents. What he found out was startling. ...
vermicious_knid said:
I want to ***STOP*** the spread of the "conspiracy theories"
Don't fucking insult my intelligence, you halfwit. You live for conspiracy theories and have posted them on a regular basis in every incarnation you've had on this site, and every time somebody points out something as simple as fucking Occam's Razor, you trot out this defender-of-freedom-and-justice canard like you're the last line between us and disaster. Do us a favor and lose your credit card number agan.
29
Cash
USA
OLD SKOOL
MAR 01, 2008 10:42 AM
If I may inject a little levity...
Can you IMAGINE how much fucking is going to happen when they find a cure for AIDS?
adjunct said:
Don't fucking insult my intelligence, you halfwit.
Please don't purport to know what my level of intelligence is. It is kind of degrading to imply that I am "half-witted." It is also a violation of the TOS.
every time somebody points out something as simple as fucking Occam's Razor, you trot out this defender-of-freedom-and-justice canard.
And rather than address and discuss the fact that the DoD admittedly engaged in a program to intentionally develop a contagious immune system suppressing infectious pathogen, you opt for a personal attack on the person who brought it up.
It is childish and intellectually dishonest. Please tell me that you are capable of higher level discourse than that.
meatbat said:
Well, several studies have found that some HUMANS, those who's ancestors survived the Black Death, in one case, have genetic immunity to AIDS. Knowing what those genes are and how they work will help us figure out ways to stop the virus. However, I hate these suggestions that we might be able to "give" people the gene. The is tough.
Really? Can you find that study and post a link? I'd be interested in reading it.
Interesting . . . seeing as how everyone who has a European, Asian, Northern African, or Middle Eastern ancestor is descended from someone who survived the Black Death. So, I'd be interested in seeing that study, too.
Interesting. I've got an ancestor who was Emperor of most of Europe at one point in time. I can't get the bug? I'm going to go shoot up while having unprotected anal sex in a Kenyan bathhouse. Been waiting about 25 years to get the green light on that move.
Thanks guys!
While I'm over there, I should stop in Nigeria to see how my friend the Prince is doing at getting his inheritance out of the country. He hasn't been so good about returning my emails after I lent him the $3000.
[David Baltimore] added: "You are quite within bounds to ask, if it's been 10 years away for 20 years, does that mean it's really never going to happen? There are people saying it will never happen."
Goddammit. I'm getting fed up with the same stupid thing every six months: "NEWFLASH: Medical Community Still Has No Fucking Clue What HIV Is or How to Stop It! Film, commentary, editorial replies and Andy Rooney snarkfest at 11!" I get it, guys - you're trying to understand a damned complex problem and efforts to make any demonstrable progress are ongoing. If the best you can do is the occasional announcement like "we've made a discovery that might lead to a discovery that might give us an HIV vaccine in time for your great-grandkids to have some totally awesome sexual experiences," however, I say get your false hope the fuck out of my newsfeed to make way for more pictures of pets in party hats and insipid musings on which Hollywood starlet has the worst boob/nosejob.
OnlyOblivion said:
I say get your false hope the fuck out of my newsfeed to make way for more pictures of pets in party hats and insipid musings on which Hollywood starlet has the worst boob/nosejob.
You know what... When you were two years old I had my first experience with a friend being diagnosed with HIV/AIDS. Today, one of my closest friends (who I met when you were only six years old) told me he had just found out he was positive.
At times, I also grow weary from the regular "Cure on the Horizon!" news. I just want them to say "Pop on down to the doctors office folks. We've got the shot!" And I must often remind myself that there are plenty of other things out there killing plenty of folks that we can actually get a grip on if we choose to. In some ways HIV/AIDS is like the cancer or heart disease of a particular generation. It started out big & scary and became the chronic & incurable illness that we just had to learn to prevent & manage.
But here's the thing... This disease has a particular bit of nastiness attached to it. It comes with socio-political symptoms & side effects. It has divided families, churches, communities, cities, governments, nations and even the medical & scientific industries tasked with finding it's cure. And that, in my opinion, has contributed more than anything to the retarded pace of research towards finding both a vaccine and an effective treatment.
So perhaps you'll forgive those of us who occasionally find our interest piqued by news of any progress, however slight it may be. Some of us out here have been dealing with this in some form or fashion for nearly three decades now. And as weary as I am of the "false hope" news, I am more weary of watching my friends become ill.
Now, if you'd rather spend your time looking at cats in party hats... please do & stay away from discussions of relevant issues.
Unfortunatly, I don't think that the yahoo article means we are any closer to a cure.
There are certain gene variations in humans that seem to have a protective effect against HIV. Most people have certain receptors on their CD4 cells. Some people, though, don't have some of these receptors because of their genetic make up (CCR5 receptors have been in the recent news). Drugs called CCR5 inhibitors have been created for this reason. They inhibit the virus from attaching to these receptors on the CD4 cell, but this is a treatment not a cure. Unfortunately there is also another receptor that HIV uses called the CXCR4 and it seems to be harder to create a drug that can block these receptors. On several different levels these drugs have been somewhat controversial, but Maraviroc was the first to be FDA approved last year http://en.wikipedia.org/wiki/Maraviroc
A good reference for HIV updates is either The Body Pro (for professionals) or The Body (for lay people) or if you really want to read scientific abstracts there is PubMed.
There are HIV vaccines in phase IIb clinical trials http://www.thebodypro.com/content/treat/art43669.html
So I can't really believe that we are "no closer to finding a vaccine" then we were in the 80's as Baltimore said. But we still a ways off.
meatbat said:
Well, several studies have found that some HUMANS, those who's ancestors survived the Black Death, in one case, have genetic immunity to AIDS. Knowing what those genes are and how they work will help us figure out ways to stop the virus. However, I hate these suggestions that we might be able to "give" people the gene. The is tough.
Really? Can you find that study and post a link? I'd be interested in reading it.
He and I saw this on the same PBS show, I think. The best I can find is a partial transcript from the show:
Dr. Stephen O'Brien of the National Institutes of Health in Washington D.C. suggests they were. His work with HIV and the mutated form of the gene CCR5, called "delta 32," led him to Eyam. In 1996, research showed that delta 32 prevents HIV from entering human cells and infecting the body. O'Brien thought this principle could be applied to the plague bacteria, which affects the body in a similar manner. To determine whether the Eyam plague survivors may have carried delta 32, O'Brien tested the DNA of their modern-day descendents. What he found out was startling. ...
Hunkpapa
United Kingdom
June 2004
MAR 01, 2008 06:04 AM