malena

When I went to san fran I had a meal at The Tonga Room at The Fairmont Hotel, it's an original Tiki bar/restaurant which has a fake rain shower inside every hour! I got drunk on half a zombie it was that strong!
I also suggest you go to the Sanrio Hello Kitty shop, Tower Records and the vintage/thrift shops at Haight and Ashbury! There's also the tattoo museum, aquarium at the pier..there's also a pirate themed shop there too!
There's a bar there called lucky 13, I didn't get a chance to go in but it looked cool!

Haight-Ashbury.
Parts of Golden Gate Park.
Chinatown for an authentic meal.
The usual touristy traps (Pier 39/Fisherman's Wharf).
The cross-streets of Union and Fillmore have a crapload of bars and clubs to hop between.
Don't know your food preferences, but there are a myriad of places to choose from.