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  • SATURDAY APRIL 9 2005 1:00 PM

Flesh Eating Drug Resistant Bug Reaches Alarming levels

Flesh eating methicillin-resistant Staphylococcus aureus (MSRA) infections have been seen outside hospitals in America. US doctors are warning people about the alarming rise in the rate of infection.

The infections in the US community have typically manifested as skin infections, such as pimples and boils, in otherwise healthy people.

Although none of the 14 patients died, they had serious complications, including the need for reconstructive surgery and prolonged stay in the intensive care unit.

The CDC has been investigating clusters of the community-acquired MRSA skin infections among athletes, military recruits and prisoners.

A common theme associated with the spread of these MRSA skin infections appears to be close skin-to-skin contact, openings in the skin such as cuts or abrasions, contaminated items and surfaces, crowded living conditions and poor hygiene.


This sounds like every student accomodation that I've ever seen. The methicillin-resistant Staphylococcus aureus is not the same as the one rampaging through UK hospitals.

In the UK, there have been some cases of MRSA in the community, but experts say these are different to the cases arising in the US.

Dr Jodi Lindsay, lecturer in infectious diseases at St George's hospital, said although no cases had been reported in the UK yet, it was a concern.

"We are worried these community-acquired MRSAs might come over here from the US," she said.

 

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traceelement

traceelement

Australia
March 2005

APR 11, 2005 12:42 AM

hahah by australian media you mean those scare mongers from ACA and Today Tonight, real respectable journalism that stuff. biggrin

Although I must admit all reports I have seen here regarding flesh eating bacteria have been about Staphylococcus aureus (MRSA) or as commonly named by the media Golden Staph.

ummm then there are the other reports and specials we get just before the onset of winter or during it (pretty much as an awareness campaign) about Meningococcus.

bean

bean

STAFF

Los Angeles, CA

APR 11, 2005 12:46 AM

Rabidnid said:

bean Um. No, it doesn't. Meningococcus bacteria is not a "flesh eating bug," and nobody other than you has claimed that anything mentioned thus far can "kill you in a day." This is the sort of rampant disregard for getting the facts straight that really annoys me to no end about this sort of story.




Meningococcus is certainly a killer in Australia to the point where they are starting to imunise against is in schools, though there is debate over the untility of that because of the diferent strains of it going around. It may not be a flesh eating virus but what was left of that girl after the amputations and surgery makes the point moot.


No, the point isn't moot, because the point was that it wasn't the same thing. Notice that I've never debated the danger posed by meningococcus. I'm not arguing that point. But that wasn't the point in the first place. One of my friends was nearly killed by spinal meningitis when we were 13. I'm intimately aware of what it can do.

You have got me interested though because a "flesh eating bug" has been doing the rounds in the media for about a decade now, though at least half of those reoprts were of meningococcus, the others are much more similar to the thing being described here, with large scale removal of surface tissue and the use of antibiotics (at least in the cases that made it into the media).


Perhaps, rather than listening to vague media reports which may or may not (and frequently do not) get the facts right, you may want to read the fact sheets about this infection, which I linked to several posts back on this page.

Here is a description of necrotizing fasciitis, which is commonly referred to as "flesh eating bacteria." It is very rare, and is caused most frequently by Streptococcus pyrogenes, not by MRSA or C-MRSA, the latter of which being the bacterium the story that prompted this thread refers to. Though, if traceelement is correct, I'd be curious about why MRSA is the culprit in those stories in your neck of the woods. Maybe it's just that the MRSA caused ones are the ones that make the news, because of the drug resistance.

[Edited on Apr 11, 2005 by bean]

bean

bean

STAFF

Los Angeles, CA

APR 11, 2005 12:51 AM

metalslut said:
and i was worried about increasing gas prices.


I think that's probably still a bigger concern. wink

dem_z

dem_z

United Kingdom
June 2004

APR 11, 2005 12:58 AM

bean said:

demetrius_z said:

bean said:
For all you people freaking out about this, here's a good fact sheet about community-acquired MRSA. Here's another one from the CDC.

The majority of cases involve infected skin lesions, and in some cases, treatment requires hospitalization. It can be treated with antibiotics, and in some cases, simply by draining the skin abscess.


How can I go around spreading panic and mayhem if you keep giving people _information_ mad wink

The MR bit of MRSA means that some antimicrobials do not work, and the list if getting smaller. eeek


Bullshit.

The MR bit of MRSA means it's resistant to methicillin. The problem with that is that methicillin is one of the more widely-used antibiotics, and it's not that it "does not work," it's that it is resistant. It can still be treated with antibiotics.


"one"?
The link that _you_ provided says "MRSA is a type of staph that is resistant to antibiotics called beta-lactams. Beta-lactam antibiotics include methicillin and other more common antibiotics such as oxacillin, penicillin and amoxicillin". How is it bullshit to say that the list of anti-microbials that are effective against MRSA is getting smaller, if the list of anti-microbials effective against MRSA _is_ getting smaller?


report


The infecting strain of MRSA was often (73 percent) resistant to prescribed antimicrobial agents. Among patients with skin or soft-tissue infections, therapy to which the infecting strain was resistant did not appear to be associated with adverse patient-reported outcomes. Overall, 23 percent of patients were hospitalized for the MRSA infection.

Conclusions Community-associated MRSA infections are now a common and serious problem. These infections usually involve the skin, especially among children, and hospitalization is common.


(Bold added)
'most' cases (nearly 3/4) are resistant to prescribed anti microbials, almost 1/4 end up in hospital, and these doctors seem to think that CA-MRSA is a "common and serious" problem.

Also, You might like to try decaf.


[Edited on Apr 11, 2005 by demetrius_z]

traceelement

traceelement

Australia
March 2005

APR 11, 2005 12:58 AM

yeah I worry about the peak oil crisis more biggrin

[Edited on Apr 11, 2005 by traceelement]

Rabidnid

Rabidnid

Australia
May 2004

APR 11, 2005 01:05 AM

See new post below

[Edited on Apr 12, 2005 6:12AM]

bean

bean

STAFF

Los Angeles, CA

APR 11, 2005 01:41 AM

demetrius_z said:

bean said:

demetrius_z said:

bean said:
For all you people freaking out about this, here's a good fact sheet about community-acquired MRSA. Here's another one from the CDC.

The majority of cases involve infected skin lesions, and in some cases, treatment requires hospitalization. It can be treated with antibiotics, and in some cases, simply by draining the skin abscess.


How can I go around spreading panic and mayhem if you keep giving people _information_ mad wink

The MR bit of MRSA means that some antimicrobials do not work, and the list if getting smaller. eeek


Bullshit.

The MR bit of MRSA means it's resistant to methicillin. The problem with that is that methicillin is one of the more widely-used antibiotics, and it's not that it "does not work," it's that it is resistant. It can still be treated with antibiotics.


"one"?
The link that _you_ provided says "MRSA is a type of staph that is resistant to antibiotics called beta-lactams. Beta-lactam antibiotics include methicillin and other more common antibiotics such as oxacillin, penicillin and amoxicillin". How is it bullshit to say that the list of anti-microbials that are effective against MRSA is getting smaller, if the list of anti-microbials effective against MRSA _is_ getting smaller?


Well, you got me on the methicillin thing. Though, I was referring to one report that I read that said that C-MRSA was more sensitive to antibacterials other than methicillin.

Nevertheless, I still contend that your statement is bullshit alarmism, for a couple reasons:

Firstly, "resistant" does not mean that "it doesn't work." It means just that, "resistant." Delivery of a complete regimen of antibiotics is listed as treatment for MRSA and C-MRSA. In addition, I haven't seen anything that says the list is getting smaller. Such information may exist, but it hasn't been mentioned in any clinical data I've seen thus far. I'm curious where you get that impression.


report


The infecting strain of MRSA was often (73 percent) resistant to prescribed antimicrobial agents. Among patients with skin or soft-tissue infections, therapy to which the infecting strain was resistant did not appear to be associated with adverse patient-reported outcomes. Overall, 23 percent of patients were hospitalized for the MRSA infection.

Conclusions Community-associated MRSA infections are now a common and serious problem. These infections usually involve the skin, especially among children, and hospitalization is common.


(Bold added)
'most' cases (nearly 3/4) are resistant to prescribed anti microbials, almost 1/4 end up in hospital, and these doctors seem to think that CA-MRSA is a "common and serious" problem.


Influenza and tuberculosis are also considered "common and serious" problems (hell, tuberculosis kills about 2 million people every year, and both diseases are airborne unlike CA-MRSA), but I'm not worried about dying from either of those, either. That which is considered "serious" to health practitioners is often something that most people need not be worried about.

Also, You might like to try decaf.


Bite me. You're trying to tell people the sky is falling and feeding them half-truths, taking a doomsday tone about an infection that causes pimples and boils in most cases and is only passed by close contact with another infected person. Tell me, how many of the cases in that study produced necrotizing faciitis? I guess "drug resistant bug that might in some rare cases result in a flesh-eating infection causes concern among doctors" wasn't quite as catchy a headline. whatever

[Edited on Apr 11, 2005 by bean]

llouys

llouys

Brazil
August 2003

APR 11, 2005 02:31 AM

demetrius_z said:
More people die of MRSA in the UK than are killed by car crashes



Really?

MistressMissy

mistressmissy

Grand Rapids, MI
March 2003

APR 11, 2005 04:19 AM

happy to be a clean freak

hungarian

hungarian

Zimbabwe
January 2005

APR 11, 2005 04:24 AM

were all gonna fucking die from disease! were all fucking dead already

hungarian

hungarian

Zimbabwe
January 2005

APR 11, 2005 04:27 AM

well.. i just finished reading a book. im scared is what i meant to say

FallFromGrace

FallFromGrace

Seattle, WA
March 2004

APR 11, 2005 05:47 AM

For kicks, try looking up Necrotizing fasciitis (or just Necrotizing) in the google image search.

yum. skull

whaa

whaa

I'm lost
November 2003

APR 11, 2005 06:24 AM

Rabidnid

Rabidnid

Australia
May 2004

APR 11, 2005 01:06 PM

louys said:

demetrius_z said:
More people die of MRSA in the UK than are killed by car crashes



Really?





A groundbreaking new treatment to combat the hospital killer bug MRSA, which is estimated to cause up to 5,000 deaths a year in Britain,





The search for new antibiotics active against "super bugs" such as MRSA is of paramount importance because of the increasing problems faced by hospitals in treating drug-resistant bacterial infections. The latest Government figures estimate that up to 100,000 people catch an infection in UK hospitals every year, with the elderly and the very young most at risk of complications and death.



Don't know if it is more than car crashs but 5,000 is a lot. The majority of the carrying-on at the moment is because of the rise in the rate of people without symtoms outside hospitals with it up to 9.2% of the sample compared to 1% 3 years previously.


link

[Edited on Apr 12, 2005 6:11AM]

dem_z

dem_z

United Kingdom
June 2004

APR 11, 2005 01:45 PM

bean said:
Nevertheless, I still contend that your statement is bullshit alarmism, for a couple reasons:

Firstly, "resistant" does not mean that "it doesn't work." It means just that, "resistant." Delivery of a complete regimen of antibiotics is listed as treatment for MRSA and C-MRSA. In addition, I haven't seen anything that says the list is getting smaller. Such information may exist, but it hasn't been mentioned in any clinical data I've seen thus far. I'm curious where you get that impression.


Splittng hairs about "resistant" and "doesn't work" is odd. Would you be happy to be treated with methicillin if you have a methicillin resistant infection? They specify a complete regimen because MRSA can kill people, they want to treat it and they don't have time to find out which particulart anti-biotic will work because some of them don't work MRSA is resistant to some of them.

A real doctor says MRSA is becoming resistant to more anti biotics
"Although the bacteria is resistant, there are still some antibiotics which work against it. Most important is one called vancomycin, although there are now reports appearing about MRSA resistant to this antibiotic too."

Some MRSA is no longer treatable by Vancomicin
""But some people get worse and can't clear it even with the antibiotic that we have got left to use against MRSA, which is called vancomycin. It's a bit more toxic and some patients don't respond and we don't know why.""

SA used to be treatable by methicillin, it isn't any more. MRSA used to be treatble by Vancomicin, but there are some strains that are resistant to vancomicin.

Conclusions Community-associated MRSA infections are now a common and serious problem. These infections usually involve the skin, especially among children, and hospitalization is common.


(Bold added)
'most' cases (nearly 3/4) are resistant to prescribed anti microbials, almost 1/4 end up in hospital, and these doctors seem to think that CA-MRSA is a "common and serious" problem.


Influenza and tuberculosis are also considered "common and serious" problems (hell, tuberculosis kills about 2 million people every year, and both diseases are airborne unlike CA-MRSA), but I'm not worried about dying from either of those, either.


You should be worried about TB if you visit the UK, especially if you spend time in London, where we have drug-resistant TB.

Also, You might like to try decaf.

Bite me. You're trying to tell people the sky is falling and feeding them half-truths, taking a doomsday tone about an infection that causes pimples and boils in most cases and is only passed by close contact with another infected person. Tell me, how many of the cases in that study produced necrotizing faciitis?


"flesh eating" - not my words.
quote from BBC (link in original article)
---
Threat of 'flesh-eating' MRSA bug
US doctors warn of small but alarming rates of a flesh-eating type of superbug.
---

I guess "drug resistant bug that might in some rare cases result in a flesh-eating infection causes concern among doctors" wasn't quite as catchy a headline. whatever




Man you're grumpy.

NEW ENGLAND JOURNAL OF MEDICINE

Necrotizing Fasciitis Caused by Community-Associated Methicillin-Resistant Staphylococcus aureus in Los Angeles
Background Necrotizing fasciitis is a life-threatening infection requiring urgent surgical and medical therapy. Staphylococcus aureus has been a very uncommon cause of necrotizing fasciitis, but we have recently noted an alarming number of these infections caused by community-associated methicillin-resistant S. aureus (MRSA).

Methods We reviewed the records of 843 patients whose wound cultures grew MRSA at our center from January 15, 2003, to April 15, 2004. Among this cohort, 14 were identified as patients presenting from the community with clinical and intraoperative findings of necrotizing fasciitis, necrotizing myositis, or both.


Underlining added.
Note they say that 29%, 4 patients, had no risk indicators.

See also the other article about MRSA.

Background Methicillin-resistant Staphylococcus aureus (MRSA) infection has emerged in patients who do not have the established risk factors. The national burden and clinical effect of this novel presentation of MRSA disease are unclear.


So you have two articles in a peer reviewed medical journal. One saying that Community aquired MRSA is becomming more common in people without established risk factors, and another saying that there is an alarming number of [necrotizing fasciitis / necrotizing myositis] caused by community-associated MRSA.

Let's have a look at what I wrote:

TECHNOLOGY: Flesh Eating Drug Resistant Bug Reaches Alarming levels
Flesh eating methicillin-resistant Staphylococcus aureus (MSRA) infections have been seen outside hospitals in America. US doctors are warning people about the alarming rise in the rate of infection.

This sounds like every student accomodation that I've ever seen. The methicillin-resistant Staphylococcus aureus is not the same as the one rampaging through UK hospitals.


Half truths and doomsday tone? Jebus, do you really need one of these?

whatever whatever

[Edited on Apr 11, 2005 by demetrius_z]

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