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  • MONDAY APRIL 16 2007 11:00 AM

Now Everyone's a Universal Donor



Do you know your blood type? In an emergency knowing could save your life. Of the four blood types, only one can be given to any patient in a transfusion -- O. It's the universal donor. Giving type A blood to a type B donor can be fatal, as the body's immune system fights against it, so if you don't know your type, and they're all out of O at the hospital, your chances of survival just went way down. All that is set to change though, as a group of scientists have discovered a way to convert all blood types to type O.

Red blood cells fall into four groups, A, B, AB, and O, according to sugars, or antigens, they have on their surface.
[...]
In a study published yesterday in the journal Nature Biotechnology, an international team of scientists describe enzymes they have found that act like miniature scissors to snip off the sugar molecules, converting all blood cells to group O.

The team leader, Henrik Clausen of the University of Copenhagen, said that giving people the wrong blood could result in severe immune reactions and even death.

"The conversion processes we describe hold promise for achieving the goal of producing universal red blood cells which would improve the blood supply while enhancing the safety of clinical transfusions," he said. Clinical trials were planned to test whether the blood treated with enzymes is safe and effective.


The promise of more blood available in our hospitals is a fantastic one, many reading this will be ineligible to give blood; in all but a handful of US states you must wait 12 months after being tattooed before you can donate, and there are other restrictions based on sexual history and even travel history, but if you are eligible why not give it a try? You might be able to save even more lives than you'd think.

 

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Comments
geo35

geo35

Minneapolis, MN
January 2003

APR 16, 2007 05:06 PM

yourfashionwar said:
i have no clue what my blood type is either.
i'm thinking A for awesome.
.



I'm A-negative, dammit...

SocietysPliers

SocietysPliers

Ocala, FL
October 2004

APR 16, 2007 05:36 PM

Being in nephrology, and dealing 50+ hours a week with hundreds dialysis patients who often need blood, this is very promising. In fact. out local hospitals have had to cancel many surgeries due to a SEVERE blood shortage. My father, who died with leukemia and treatment-related anemia could possibly have benefited from discoveries that are certain to spin off from this discovery.

Also, I wonder if this process could aid in compatibility for donors (the vast majority of my patients never get kidneys).

I have to check into this more.

Great article, AF. In your honour I am putting in the DVD of the movie that was doubtlessly named after you.

Eta

Eta

Portland, OR
November 2005

APR 16, 2007 06:30 PM


in all but a handful of US states you must wait 12 months after being tattooed before you can donate



Not sure which states are in that "handful" but I live in Oregon and you don't have to wait, as long as your tattoo was done with a sterilized needle by a licensed artist.

MrCrisp

MrCrisp

I'm lost
August 2004

APR 16, 2007 06:56 PM

O snap!

Oninotaki

oninotaki

Ypsilanti, MI
March 2003

APR 16, 2007 07:59 PM

MistressMissy said:
I'm one of those people who has no fucking clue what their blood type is.



So am I.

While I was in japan I was asked all the time, to which I could only answer I dont know. Almost everyone that asked was horrified at my answer blush

Necia

Necia

San Francisco, CA
August 2005

APR 16, 2007 08:08 PM

MrCrisp said:
O snap!



Hey-O!




. . . Hehehe. So easy! And so amusing!

Necia

Necia

San Francisco, CA
August 2005

APR 16, 2007 08:11 PM

I thought it was only O negative that was the universal donor. I'm O positive, and I'm pretty sure I was told that my blood works for 85% of people, but it's only O negative that's the universal one.

But yeah, I'm with johaanfaust: he feels 100% less special now, but I feel at least 85% less special now.

On the upside, though, I don't have to feel as guilty about not being able to give blood for six months when I get new piercings.

Subrosa

Subrosa

San Francisco, CA
July 2004

APR 16, 2007 08:17 PM

Necia said:
I'm O positive,



Me too!

Cassiel

Cassiel

Aurora, CO
September 2004

APR 16, 2007 08:19 PM

O+

apesamongus

apesamongus

Atlanta, GA
July 2002

APR 16, 2007 08:26 PM

Necia said:
I thought it was only O negative that was the universal donor. I'm O positive, and I'm pretty sure I was told that my blood works for 85% of people, but it's only O negative that's the universal one.

But yeah, I'm with johaanfaust: he feels 100% less special now, but I feel at least 85% less special now.

On the upside, though, I don't have to feel as guilty about not being able to give blood for six months when I get new piercings.


This benefits us Os the most since we're the only ones who can only recieve O. Those ABs don't get anything out of the deal. I'm all for being less special in exchange for having more blood available for me if I need it.

XamaX_is_Dead

XamaX_is_Dead

La Mesa, CA
March 2007

APR 17, 2007 03:30 PM

this reminds me of a pick up line my buddy once used jokingly, which was "i love you, what's your blood type?" if you were there it was pretty hilarious. i just thought of that since most of the people are sharing their blood type.

_DictionaryGirl_

_DictionaryGirl_

NEWSWIRE

San Diego, CA

APR 17, 2007 03:40 PM

Subrosa said:

Necia said:
I'm O positive,



Me too!



Aww get a room and quit transfusing all over the internets! tongue

goodpoltergeist

goodpoltergeist

Douglasville, GA
January 2007

APR 20, 2007 08:42 AM

I'd really love to give blood, but I got a tattoo in november so I'm still ineligible...

for now...

I also don't know my blood type, because I've never been told (although with the amount of blood work I've had done, I really don't think it would've been that big a deal for them to type me while they were at it...) that's part of the reason I want to give blood, so they can type me!

Towelly

Towelly

Philadelphia, PA
January 2007

APR 20, 2007 10:36 AM

yourfashionwar said:
i have no clue what my blood type is either.
i'm thinking A for awesome.

i plan to donate blood as soon as i am able.
for a long time i didn't meet the weight requirement, now that i do i have to stop getting tattoos for awhile.



Blood type is a categorization of blood based on surface characteristics of blood cells. It's been a while since I went over this, but as I understand it, blood and body cells in each person carry a series of markers that effectively shortcut the infection-fighting process; if a white blood cell chances across one of your other cells and recognizes the markers, it recognizes the cell as friendly and doesn't attack it. This might not (and probably isn't) what those markers are for, but it's the important thing to note so far as blood donation is concerned, because if you pump blood with the wrong markers in, white blood cells from the body will recognize the new blood as foreign and attack it.

There were originally thought to be two types of factors, called A and B (O signifies the absence of either, AB signifying the presence of both), but blood donations still suffered a 15% rejection rate. They discovered the reason was a third factor, called the Rh factor, hence the addition of a + or - to indicate presence of the factor. Having AB+, then, means you have all 3 factors and are effectively a universal recipient, because your body will accept blood and tissue with any factors and not reject it (it should be noted that while white blood cells will attack tissue/blood with foreign factors, the absence of those factors will not trigger a response), while a O- is a universal donor, because anyone can accept their tissue/blood and not reject it.


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