Good bands with female singers

L7 for sure.

i use to really like a group called bikini kill.

You can't forget Siouxse and the Banshees or Switchblade Symphony!!!

The Pretty Reckless

This is perfect...I understand what the OP was wanting and I looked through most everything posted and this meets the description of what I am looking for.

Thank you so much, now I have a new band to listen to.

Bratmobile and Bikini Kill are among my favorites of all time in any genre.

I've always wanted a vinyl copy of GhettoBlaster, by the Red Aunts, because it fucking rocks.

I'm also seeing The Muffs, on the 28th, here in San Diego.

Sister Sin
Nightwish
Kittie
Sirenia
Epica
Within Temptation

PRE's crazy assed music video. The song starts about two minutes in....

Pre: Teenage Lakes

Pre: Fuk Is Fun. This one is live, just for fun, live!

Relatively new bands out there:

Billy the Kid (www.billythekidonline.com)
Shoppers
White Lung
Foreign Objects

I've probably missed it but Brody Dalle - Spinerette & The Distillers

ACID KING.

ARKONA
My Brightest Diamond
Fiery Furnaces
Kylesa
St. Vincent
The Dirty Projectors
Deradoorian
The Coathangers
Ladytron
Melt Banana

They ain't NIN but I love Warpaint.

Probably already been said, but I'll post them.

Jack Off Jill
Lacuna Coil
Within Temptation
Scarling

These are a few metal bands if your looking to explore into into another realm.
Nightwish and their last album Imaginarium.
Therion
Midnattsol
Cruachan
Visions of Atlantis
Edenbridge

Let's see... Shiny Toy Guns, The Birthday Massacre, In This Moment, Emilie Autumn, Jakalope, Collide, Curve, i:scintilla, KMFDM has several female vocalists... I've got a whole pandora station full called Sirens of Synth.

Fever ray, ladytron

Ayria,Angelspit, Ego Likeness, Autumns Grey Solace, Tearwave, Joy Shannon & The Beauty Marks, Unsun, Katra, Stream of Passion, Angelzoom, Delain, Claire Voyant, Cocteau Twins, Razor Skyline, Sunshine Blind, Coptic Rain, Android Lust, Deathride 69, Thrive, Fading Colours, Battery, Randolph's Grin, Regenerator, Attrition, Waiting for God, Venus Walk, Hanzel und Gretyl, This Ascension, Makaras Pen, Memoira, Mira, Newskin, Soma, Per Somnia, Hungry Lucy, Prosper Falls, Paul Averginos, Kei Kusama, Daughter Darling, Sarah Fimm, Silverman, Edgepilotz, Jacoo, Girl Next Door, Lotus, Omega Lithium, Sapphire Solace, Sarah Renfro, Stolen Babies, Switchblade Symphony, The Shroud, We Are the Fallen, Alice in Videoland, Bow Ever Down, Client, Freeze Pop, Fright Doll, Miss FD, Helalyn Flowers, How to Destroy Angels, Santa Hates You, Spectra Paris, Waves Under Water, Stray, Unter Null, Astarte, Within Temptation, In This Moment, Lacuna Coil, Kittie, Otep, Emilie Autumn, The Birthday Massacre, I:scintilla, Collide, Sirenia, Epica, Nightwish, Halestorm, Gretchen, Delerium and so on...

have you tryed how to destroy angles?

Polica , fronted by Channy Casselle . Two other bands she sang with were Roma di Luna and Gayngs. Her voice is beautiful and ethereal .

iwrestledabearonce is really great
its not NIN by any means but still worth a look

Alabama Shakes (Brittany Howard....AMAZING) and Wild Flag (Carrie Brownstein or Mary Timoney...both AMAZING)

Here are some of my electronic/pop contributions:

Anavan
CSS
Chiasm
Dandi Wind
Flesh Field
Hanin Elias
Helanyn Flowers
Kap Bambino
Kerli
Miss Kittin
Neikka RPM
Parralox
Pr0metheus Burning
Pzychobitch
Robots In Disguise
Tying Tiffany
Zombie Girl