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wendoo

wendoo

United Kingdom
February 2006

MAY 27, 2006 05:19 AM

I'm not sure about in the long term, but SSRIs will block the euphoric effects of ecstasy as they have already increased the amount of serotonin in the synapse and blocked the reuptake receptors.
Some studies suggest the nerve damage could be due to toxic metabolites of MDMA, so if this is true the SSRI will not prevent the damage as the MDMA will still be broken down into the same metabolites eventually.

Astrobouy

Astrobouy

United Kingdom
July 2005

MAY 27, 2006 05:52 AM

wendoo said:
I'm not sure about in the long term, but SSRIs will block the euphoric effects of ecstasy as they have already increased the amount of serotonin in the synapse and blocked the reuptake receptors.
Some studies suggest the nerve damage could be due to toxic metabolites of MDMA, so if this is true the SSRI will not prevent the damage as the MDMA will still be broken down into the same metabolites eventually.




Yep. I was on SSRIs for 6 months last year, and continued to take mdma occasionally, but the euphoria was gone completely. The stimulant effect was still there, but no rushes. When I came of the SSRI it was like doing it for the first time again, lovely.

lovelysitwell

lovelysitwell

United Kingdom
July 2005

MAY 27, 2006 02:29 PM

i think the come down isnt as harsh while taking ssri as well but it could just be the effect it had on me?

CaptainJonny

CaptainJonny

United Kingdom
April 2006

MAY 27, 2006 02:47 PM

wendoo said:
I'm not sure about in the long term, but SSRIs will block the euphoric effects of ecstasy as they have already increased the amount of serotonin in the synapse and blocked the reuptake receptors.
Some studies suggest the nerve damage could be due to toxic metabolites of MDMA, so if this is true the SSRI will not prevent the damage as the MDMA will still be broken down into the same metabolites eventually.



Dammit, why d'you have to be so smart all the time? wink

CharlieLove

CharlieLove

Fiji
March 2006

MAY 27, 2006 02:56 PM

took pure form once, never again.

i can't do uppers or things that make me feel "happy".

then i'll have no will to stop.

Roethke

Roethke

SUICIDEGIRL

California, USA

MAY 27, 2006 07:06 PM

I've never done it, but I hate being around people who are on ecstacy. Watching kittens act like kittens is cute, watching adults act that way is grotesque.

So, I just avoid situations with people on it. I won't spoil your rave.

MrStitches

MrStitches

Brooklyn, NY
November 2003

MAY 27, 2006 07:31 PM

acid is better maaaaaan.

Carmen

Carmen

SUICIDEGIRL

New York, USA

MAY 27, 2006 08:52 PM

I enjoy it. I used to be a fairly heavy user a few years ago (as in at least 4 times a month for 6 months) but our town kind of dried up in the late 90s and its been slim pickins since. I've done it 3 or 4 times over the past 2 years- one of which was amazing, the others were mediocre. I dont know if its the quality (which was suspect) or me growing out of it that has made it crappier, but I'm ok with it either way. it was a fun stint.
I'm still a raver at heart, though.


OH and to answer the guy who asked about how long to wait between rolls- I would say that once a month is about the most you should use to avoid any serious long-term damage AND to maximize your experience. Your body can only produce serotonin so fast, so if you're rolling back-to-back, your second one is going to be crappier. I read somewhere that it only takes like 9 days for your body to recoup its serotonin and dopamine stores, but I'm not sure if I believe that. Either way, waiting a month at least is sure ti allow your body a decent amount of time to at least ALLOW you to have the feeling again- whether you will or not is totally independent of that.

Quarie_glitter

Quarie_glitter

Australia
September 2008

SEP 22, 2008 05:50 AM


MDMD im fairly certain isnt toxic.
nobody has died from taking pure mdma.

research on erowid.
alcohol is so much more dangerous, and its legal. mdma is a beautiful substance, why it was made illegal is beyond me. if you research the history you can see for yourself - nothing bad was coming out of its production. the american government, on the other hand, was not making any money from it.. and supprise supprise.. suddenly prohibited.

gah. dont get me started.
i think 100 percent it should be legalised. pure mdma, which is "ecstasy" is an empathogen and an enactogen, equalling a truly wonderous substance that is truly a great tool. i am so thankful for the longterm change in perception it has granted me. im sure many of you will understand what i mean here; it opens doors. lets you view your life with humility and greatfulness, with new eyes.

out of good and evil drugs, it is good.

_Crystal_

_Crystal_

Australia
August 2007

SEP 22, 2008 06:08 AM

I recently found out that a guy I used to friends with at school had a heart attack because he was taking so much ecstasy. He's only 19.
I've never tried it, an after hearing that I don't think I ever will. surreal

Squire

Squire

I'm lost
November 2003

SEP 22, 2008 07:17 AM

Astrobouy said:

wendoo said:
I'm not sure about in the long term, but SSRIs will block the euphoric effects of ecstasy as they have already increased the amount of serotonin in the synapse and blocked the reuptake receptors.
Some studies suggest the nerve damage could be due to toxic metabolites of MDMA, so if this is true the SSRI will not prevent the damage as the MDMA will still be broken down into the same metabolites eventually.



Yep. I was on SSRIs for 6 months last year, and continued to take mdma occasionally, but the euphoria was gone completely. The stimulant effect was still there, but no rushes. When I came of the SSRI it was like doing it for the first time again, lovely.



I have learned something today.

SnakePlissken

SnakePlissken

Corvallis, OR
December 2002

SEP 22, 2008 10:57 AM

Quarie_glitter said:

MDMD im fairly certain isnt toxic.
nobody has died from taking pure mdma.



Link please.


research on erowid.
alcohol is so much more dangerous, and its legal. mdma is a beautiful substance, why it was made illegal is beyond me. if you research the history you can see for yourself - nothing bad was coming out of its production. the american government, on the other hand, was not making any money from it.. and supprise supprise.. suddenly prohibited.



I doubt it was a vast conspiracy but more a reaction to the criminal production of a substance that was originally designed to be used medically. Just like so many other substances that crossed the line from legitimate use to recreation.


And, for the record, any drug that promotes techno music is inherently evil.

Cassiel

Cassiel

Aurora, CO
September 2004

SEP 22, 2008 01:32 PM

"A drug that makes you love everybody? Sounds like hell to me."

~ John Waters

Afua

Afua

Duluth, GA
January 2008

SEP 22, 2008 01:46 PM

DickieV said:

dustinOMG said:
The next day really sucks ass.

How often is it "safe" to do it?


Yeah, It does suck ass, I used to say is stripped your soul away and it took a couple of days to come back.



Sounds about right. years ago i was at a party and i asked someone for advil cuz i had a migraine and i took two of them -- she confused her beat pills for her real shit and i was in trouble.

i'd like to try it again in a safe environment ( like at home) but only once. i've got too many comics to draw to feel fucked up in the morning. puke

lifeinrewind

lifeinrewind

I'm lost
OLD SKOOL

SEP 22, 2008 04:08 PM

I haven't seen good X in 8 years at least

Thistle

Thistle

SUICIDEGIRL

California, USA

SEP 24, 2008 08:10 PM

Quarie_glitter said:

MDMD im fairly certain isnt toxic.
nobody has died from taking pure mdma.

research on erowid.
alcohol is so much more dangerous, and its legal. mdma is a beautiful substance, why it was made illegal is beyond me. if you research the history you can see for yourself - nothing bad was coming out of its production. the american government, on the other hand, was not making any money from it.. and supprise supprise.. suddenly prohibited.

gah. dont get me started.
i think 100 percent it should be legalised. pure mdma, which is "ecstasy" is an empathogen and an enactogen, equalling a truly wonderous substance that is truly a great tool. i am so thankful for the longterm change in perception it has granted me. im sure many of you will understand what i mean here; it opens doors. lets you view your life with humility and greatfulness, with new eyes.

out of good and evil drugs, it is good.



Alcohol is only dangerous when people drink too much and do stupid things while drinking. MDMA would be dangerous in exactly that way if it were legal.

Out of everyone who drinks, very few people die just from drinking too much.

Suri

Suri

SUICIDEGIRL

Pennsylvania, USA

SEP 24, 2008 08:17 PM

Salome said:
I've taken it twice, and all I did was lie on the grass outside the venue and say "I can FEEL the music through the GROUND!"



ha! true.

Perdita

Perdita

SUICIDEGIRL

I'm lost

SEP 25, 2008 04:42 PM

Salome said:
I've taken it twice, and all I did was lie on the grass outside the venue and say "I can FEEL the music through the GROUND!"



Haha I remember someone I know still rolling the next day and stroking peoples' legs telling them their pants felt amazing.

silversoul7

silversoul7

Portland, OR
January 2008

SEP 25, 2008 04:54 PM

It's about the only drug I'll still do, and still one of my all-time faves. It has lost its magic a little bit, though. I doubt it'll ever be as good as my first time.

Eric_Only

Eric_Only

Princeton, NJ
January 2005

SEP 27, 2008 02:09 PM

MrStitches said:
acid is better maaaaaan.



holla!!!!

biggrin

Eric_Only

Eric_Only

Princeton, NJ
January 2005

SEP 27, 2008 02:10 PM

silversoul7 said:
I doubt it'll ever be as good as my first time.



you'll never get as high as you did the first time. with any substance.



EL SUICIDO LOCO

Amy__

Amy__

United Kingdom
May 2007

SEP 28, 2008 12:05 PM

I loved it at 5am when I took 2. I didn't love it at 8am when I left for work. And I don't love it now at 8pm while I'm still in work.
Urgh, I feel grim. Now I remember why I stopped taking it.

MrStitches said:
acid is better maaaaaan.



It so is biggrin
R.I.P Dr.Albert Hofmann, you absolute genius.

CheshireCat

CheshireCat

Los Angeles, CA
January 2004

SEP 28, 2008 01:53 PM

I was shrooming in a room of people on X, needless to say we were inhabiting two very different worlds. I think I prefer doing special K to ecstasy ...though I cannot even handle that any more.Only the mushroom for me now.

silversoul7

silversoul7

Portland, OR
January 2008

SEP 28, 2008 10:16 PM

Mr_Miserable said:

silversoul7 said:
I doubt it'll ever be as good as my first time.



you'll never get as high as you did the first time. with any substance.



EL SUICIDO LOCO


Not true. When I first started smoking pot, I was getting schwag. It was only later that I started getting the chronic.

DhD_No_Pants

DhD_No_Pants

Katy, TX
May 2006

SEP 28, 2008 11:12 PM

I got caught up in it quite a few years ago. I loved it too much, which is why I quit taking it. Strangely enough, one of the things I miss most about it was how amazing it could feel to just breathe, and how easy it was to sit down with someone and talk to them. Not to get all crazy hippie about it, but it was incredible how you could sit there with someone and listen to the bad things and the good things in their life, and really understand how they felt. It also allowed me to talk about and release a lot of the dark parts of my life that I had never been brave enough to talk about before.

I read up on how it was used in therapy back in the day, and I can completely understand how that would work. I think about half of the times I rolled, my friends and I ended up in these strange therapy sessions with each other.

We attempted to be responsible with it. We always did it in even numbers and had a 'rolling buddy' We made sure our buddy drank plenty of water, didn't overexert themselves, didn't run naked through the apartments, etc. Helped each other through when it got overwhelming, and gave plenty of massages. haha. Ohhh, to be young and stupid again!

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