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Proco

Proco

United Kingdom
May 2008

NOV 10, 2008 04:42 PM

first obama, now a cure for aids?

whats next...are they going to discover a unicorn?

everything is going swimmingly tongue

sick

sick

Minneapolis, MN
June 2003

NOV 10, 2008 05:32 PM

magpieboy said:
I was going to say the same thing. There's ego involved, here! That's worth more than any corporatesuit's bonus!



Exactly. Any scientist who's any good cares more about the recognition than the money.

Maxx

maxx

Los Angeles, CA
July 2002

NOV 10, 2008 05:39 PM

unprotected sex, here i come!

Quella

Quella

USA
July 2008

NOV 10, 2008 10:25 PM

Sick said:

magpieboy said:
I was going to say the same thing. There's ego involved, here! That's worth more than any corporatesuit's bonus!



Exactly. Any scientist who's any good cares more about the recognition than the money.



True, or they'd have sold out to the drug companies, rather than slaving and grant writing and living on more modest incomes.

Cosi

Cosi

Los Angeles, CA
December 2006

NOV 11, 2008 09:15 AM

This is very very cool. There have actually been a couple of weird cases where a patient with AIDS has suddenly dropped from AIDS status, back down to HIV very suddenly. My friend who has had the disease for about 15 years now, has gone back and forth between being very very very sick, to the doctors hardly seeing the disease in her body at all. And she didn't even start taking antiretrovirals until about 5 years ago or something. I know there is an article about her somewhere, I will try and find it.

In any case, it is great to see steps in the right direction for this terrible disease.

SockPuppet

SockPuppet

I'm lost
July 2006

NOV 11, 2008 03:29 PM

Maxx said:
unprotected sex, here i come!



One word: herpes.

sick

sick

Minneapolis, MN
June 2003

NOV 11, 2008 03:48 PM

SockPuppet said:

Maxx said:
unprotected sex, here i come!



One word: herpes.



Pfft...that's not a serious disease. Mostly inconvenient and embarrassing.

Edit: That was somewhat insensitive. I know it's emotionally distressing and such. I meant it's not (generally) fatal.

SockPuppet

SockPuppet

I'm lost
July 2006

NOV 11, 2008 04:03 PM

Sick said:

SockPuppet said:

Maxx said:
unprotected sex, here i come!



One word: herpes.



Pfft...that's not a serious disease. Mostly inconvenient and embarrassing.

Edit: That was somewhat insensitive. I know it's emotionally distressing and such. I meant it's not (generally) fatal.



Certainly. (Is it ever fatal?)

It does make it harder to get laid, though.

Katieesq

Katieesq

USA
June 2008

NOV 11, 2008 04:06 PM

SockPuppet said:

Sick said:

SockPuppet said:

Maxx said:
unprotected sex, here i come!



One word: herpes.



Pfft...that's not a serious disease. Mostly inconvenient and embarrassing.

Edit: That was somewhat insensitive. I know it's emotionally distressing and such. I meant it's not (generally) fatal.



Certainly. (Is it ever fatal?)

It does make it harder to get laid, though.



Yes - if you contract Herpes simplex encephalitis.


Herpes simplex encephalitis is a severe brain infection; in the absence of effective antiviral therapy, mortality is in excess of 70%, and only about 2.5% of patients overall regained normal neurologic function (Whitley and Lakeman 1995). The prognosis is better when antiviral therapy is initiated relatively early in the course of disease; a French study showed a favorable outcome in 65% of patients (55 of 85) and complete recovery in 14% (12 of 85) (Raschilas et al 2002).Young patients (less than 30 years old) also have a more favorable outcome than older patients. Treatment initiated after consciousness is severely impaired is unlikely to result in a good clinical outcome (Whitley et al 1977). Even with appropriate acyclovir therapy, only 38% of patients had mild or no neurologic impairment (Whitley et al 1986). Persistent cognitive and memory impairment, aphasia, and motor deficits are common after herpes simplex encephalitis. Chronic seizure disorders may also occur. Recurrent or relapse of herpes simplex encephalitis occurs in up to 5% to 10% of patients.



Quoted from Medlink Neurology. Brain herpes is the worst.

SockPuppet

SockPuppet

I'm lost
July 2006

NOV 11, 2008 04:09 PM

Katieesq said:

SockPuppet said:

Sick said:

SockPuppet said:

Maxx said:
unprotected sex, here i come!



One word: herpes.



Pfft...that's not a serious disease. Mostly inconvenient and embarrassing.

Edit: That was somewhat insensitive. I know it's emotionally distressing and such. I meant it's not (generally) fatal.



Certainly. (Is it ever fatal?)

It does make it harder to get laid, though.



Yes - if you contract Herpes simplex encephalitis.


Herpes simplex encephalitis is a severe brain infection; in the absence of effective antiviral therapy, mortality is in excess of 70%, and only about 2.5% of patients overall regained normal neurologic function (Whitley and Lakeman 1995). The prognosis is better when antiviral therapy is initiated relatively early in the course of disease; a French study showed a favorable outcome in 65% of patients (55 of 85) and complete recovery in 14% (12 of 85) (Raschilas et al 2002).Young patients (less than 30 years old) also have a more favorable outcome than older patients. Treatment initiated after consciousness is severely impaired is unlikely to result in a good clinical outcome (Whitley et al 1977). Even with appropriate acyclovir therapy, only 38% of patients had mild or no neurologic impairment (Whitley et al 1986). Persistent cognitive and memory impairment, aphasia, and motor deficits are common after herpes simplex encephalitis. Chronic seizure disorders may also occur. Recurrent or relapse of herpes simplex encephalitis occurs in up to 5% to 10% of patients.



Quoted from Medlink Neurology



Ouch.
And how does one contract Herpes simplex encephalitis ??

Katieesq

Katieesq

USA
June 2008

NOV 11, 2008 04:12 PM

Well, SockPuppet,


Primary infection with herpes simplex virus in susceptible (seronegative) individuals occurs after exposure of the virus to a mucosal surface or abraded skin. The virus is subsequently transported along axons via retrograde transport to nuclei of neurons in local peripheral sensory (trigeminal or dorsal root) ganglia. The viral genome remains in a latent state in peripheral sensory ganglia for the life of the host. A variety of stimuli, including physical or emotional stress, fever, menstruation, or ultraviolet light, cause reactivation of the virus with viral gene expression and the development of recurrent infections, most commonly skin lesions (eg, cold sores). The majority of the population becomes infected with herpes simplex virus-1 by age 40. Most herpes simplex virus-2 infections are sexually transmitted; women and African Americans have higher infection rates than men and Caucasians, respectively.

The localization of herpes simplex encephalitis in temporal lobes and orbitofrontal cortex may, in part, reflect the route of entry of the virus into the host. In primary infection, the virus may enter by an olfactory route and spread along olfactory fibers through the cribriform plate into the olfactory bulbs. Subsequently, viral spread could occur along the base of the brain. At least half of cases of herpes simplex encephalitis are caused by a different viral strain than the one responsible for cold sores (Whitley et al 1982a). In reactivation of herpes simplex virus infection, it has been hypothesized that the virus may spread from the trigeminal ganglion along branches of the trigeminal nerve in tentorial nerves that innervate the meninges of the anterior and middle cranial fossae (Davis and Johnson 1979). In situ reactivation of latent virus from brain tissue, where it sometimes can be detected, remains another possibility (Baringer and Pisani 1994).



So get tested, or else you'll get brain herpes!

Maxx

maxx

Los Angeles, CA
July 2002

NOV 11, 2008 04:14 PM

words words words.
key party. this saturday. my place.

_grrlhavoc_

_grrlhavoc_

New York, NY
November 2008

NOV 11, 2008 04:16 PM

It migrates up your olfactory or trigeminal nerve in your face into your brain after a herpes breakout...fun

sick

sick

Minneapolis, MN
June 2003

NOV 11, 2008 04:30 PM

Katieesq said:

SockPuppet said:

Sick said:

SockPuppet said:

Maxx said:
unprotected sex, here i come!



One word: herpes.



Pfft...that's not a serious disease. Mostly inconvenient and embarrassing.

Edit: That was somewhat insensitive. I know it's emotionally distressing and such. I meant it's not (generally) fatal.



Certainly. (Is it ever fatal?)

It does make it harder to get laid, though.



Yes - if you contract Herpes simplex encephalitis.

SPOILERS! (Click to view)


Herpes simplex encephalitis is a severe brain infection; in the absence of effective antiviral therapy, mortality is in excess of 70%, and only about 2.5% of patients overall regained normal neurologic function (Whitley and Lakeman 1995). The prognosis is better when antiviral therapy is initiated relatively early in the course of disease; a French study showed a favorable outcome in 65% of patients (55 of 85) and complete recovery in 14% (12 of 85) (Raschilas et al 2002).Young patients (less than 30 years old) also have a more favorable outcome than older patients. Treatment initiated after consciousness is severely impaired is unlikely to result in a good clinical outcome (Whitley et al 1977). Even with appropriate acyclovir therapy, only 38% of patients had mild or no neurologic impairment (Whitley et al 1986). Persistent cognitive and memory impairment, aphasia, and motor deficits are common after herpes simplex encephalitis. Chronic seizure disorders may also occur. Recurrent or relapse of herpes simplex encephalitis occurs in up to 5% to 10% of patients.



Quoted from Medlink Neurology. Brain herpes is the worst.



You are correct, miss. Neonatal HSV infections are also incredibly dangerous.


So get tested, or else you'll get brain herpes!



I know I have herpes. I just have to be careful not to touch a cold sore then pick my nose.

Otoki

Otoki

SUICIDEGIRL

Minnesota, USA

NOV 12, 2008 12:00 AM

It's amazing how annoying oral herpes can be. I've had cold sores since I was ten, and even that cuts into my sex life because I don't want my partner to get this fucking annoying virus, so if I even THINK I'm getting a cold sore I don't kiss or, well, anything else. It sucks (or, rather, doesn't, ifyaknowwhatImean *nudge nudge*)

FellOnEarth

FellOnEarth

Temecula, CA
April 2006

NOV 12, 2008 12:10 AM

I was under the impression that most people have the simple form of herpes (of the cold sore variety, HSV1) and many contract it at a fairly young age. If this is the case, Otoki, you simply need to ask your partner if he or she has ever had a cold sore. Yeah it can be a bit of a turn off, but it can also mean you're free to free Willy or Walter (On Golden Pond reference). blush Well, you actually might want to consider other nasties out there too, in fact you may want to know a lot of other things about your potential partner before swapping fluids too.

On second thought (and after looking it up), you can transfer the virus to other parts of the body, sooo... Probably a good idea to refrain from any extra curricular activities during an cold-sore outbreak to prevent further outbreaks to yourself and others.

sick

sick

Minneapolis, MN
June 2003

NOV 12, 2008 05:09 AM

FellOnEarth said:
I was under the impression that most people have the simple form of herpes (of the cold sore variety, HSV1) and many contract it at a fairly young age.



In the US, something like 68% of people have HSV1.

Otoki said:
It sucks (or, rather, doesn't, ifyaknowwhatImean *nudge nudge*)



Snap snap, grin grin, wink wink, nudge nudge, say no more?

SPOILERS! (Click to view)

Fast forward to about 1:30.

Otoki

Otoki

SUICIDEGIRL

Minnesota, USA

NOV 12, 2008 11:19 AM

FellOnEarth said:
I was under the impression that most people have the simple form of herpes (of the cold sore variety, HSV1) and many contract it at a fairly young age. If this is the case, Otoki, you simply need to ask your partner if he or she has ever had a cold sore. Yeah it can be a bit of a turn off, but it can also mean you're free to free Willy or Walter (On Golden Pond reference). blush Well, you actually might want to consider other nasties out there too, in fact you may want to know a lot of other things about your potential partner before swapping fluids too.

On second thought (and after looking it up), you can transfer the virus to other parts of the body, sooo... Probably a good idea to refrain from any extra curricular activities during an cold-sore outbreak to prevent further outbreaks to yourself and others.


Not only can the virus be tranferred to other parts of the body, but my boyfriend is one of those lucky jerks who has never had a cold-sore. Also, on the buzzkill note, we show each other our STD test results. Yeah. I'm a nerd.

sick

sick

Minneapolis, MN
June 2003

NOV 12, 2008 04:39 PM

Otoki said:
Not only can the virus be tranferred to other parts of the body, but my boyfriend is one of those lucky jerks who has never had a cold-sore. Also, on the buzzkill note, we show each other our STD test results. Yeah. I'm a nerd.



He's never had a cold sore? What an asshole.

As for sharing test results, they probably don't test for herpes simplex anyway. The useful tests are expensive, and my understanding is they typically only use them when there's reason to suspect someone actually has herpes. The blood test, though less expensive, is more or less useless, because it doesn't differentiate between HSV-1 and HSV-2.

That is, since you get cold sores, you'd be explaining to your boyfriend why you tested positive for herpes. Wouldn't that be fun?

Me, I'm opposed to swapping bodily fluids. Contamination, you know.

soulcompromise

soulcompromise

I'm lost
November 2006

NOV 12, 2008 08:14 PM

Fantastic! Sounds like a pretty marvelous breakthrough. eeek

Otoki

Otoki

SUICIDEGIRL

Minnesota, USA

NOV 12, 2008 08:35 PM

Sick said:

Otoki said:
Not only can the virus be tranferred to other parts of the body, but my boyfriend is one of those lucky jerks who has never had a cold-sore. Also, on the buzzkill note, we show each other our STD test results. Yeah. I'm a nerd.



He's never had a cold sore? What an asshole.

As for sharing test results, they probably don't test for herpes simplex anyway. The useful tests are expensive, and my understanding is they typically only use them when there's reason to suspect someone actually has herpes. The blood test, though less expensive, is more or less useless, because it doesn't differentiate between HSV-1 and HSV-2.

That is, since you get cold sores, you'd be explaining to your boyfriend why you tested positive for herpes. Wouldn't that be fun?

Me, I'm opposed to swapping bodily fluids. Contamination, you know.


They do test for it if you ask for a comprehensive test (rather than just gonorrhea/chlamidia). I think you're right about it not differentiating between the strains, thought.

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